Tools and technologies supporting advanced life-science research
Allied Biotechnology brings research laboratories, universities and life-science R&D teams in India a growing portfolio of research tools, starting with cell-specific extracellular vesicle (EV) capture plates for EV enrichment and downstream molecular analysis.
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An introduction to EVs and why researchers study them
Extracellular vesicles (EVs) are small, membrane-bound particles released by cells into their surroundings. They are not cells themselves. EVs can carry cargo such as proteins and nucleic acids, and they are found in a range of biological fluids.
Because EVs carry molecular cargo from the cells that release them, they are an active area of life-science research, including studies of cell-to-cell communication and exploratory biomarker research.
A biological sample contains a mixed population of EVs released by many different cell types. Cell-specific EV capture uses affinity-based capture on a pre-coated plate to enrich EV populations associated with a selected cell type, through compatible surface targets.
The enriched EVs can then be used for research analysis of EV-associated proteins and/or nucleic acids, depending on the downstream assay and protocol chosen.
Affinity capture enriches EV populations associated with a cell type; it does not by itself prove the exact cell of origin. Target performance should be validated for each application.
A simple four-step research workflow
Prepare or enrich the EV-containing sample.
Add the sample to the selected cell-specific capture plate.
Incubate, then wash to remove unbound material.
Analyse captured EV-associated proteins or nucleic acids.
The exact protocol varies by product. Always follow the approved product datasheet.
Potential areas of investigation for cell-specific EV enrichment
Exploratory research into EV-associated molecular markers.
Exploratory studies of EVs in biological fluids.
Research on EV populations associated with immune cells.
Analysis of EV-associated protein and nucleic-acid cargo.
These are research applications only. The products are not intended to diagnose disease, predict outcomes or provide clinical results.
EVHook cell-specific EV capture plates
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T cells
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with T cells.
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B cells
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with B cells.
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Macrophages
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with macrophages.
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Microglia
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with microglia.
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Neurons
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with neurons.
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Astrocytes
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with astrocytes.
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Pancreatic beta cells
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with pancreatic beta cells.
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Endothelial cells
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with endothelial cells.
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Epithelial cells
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with epithelial cells.
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Adipocytes
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with adipocytes.
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Cardiomyocytes
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with cardiomyocytes.
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Hepatocytes
Pre-coated capture plate for affinity-based enrichment of extracellular vesicle populations associated with hepatocytes.
View DetailsFor Research Use Only (RUO). Not for use in diagnostic procedures.
Research laboratories, universities, diagnostic R&D teams and life-science researchers: contact Allied for product information, availability and technical enquiries.
Send an Enquiry +91-9699918275